RNA-Seq Blog· RNA-Seq Blog·· 4 天前AI 评分58
研究揭示 STAT2 异常剪接与肺癌免疫治疗响应相关
Overlooked ‘off switch’ in lung tumors may explain why immunotherapy doesn’t work for everyone
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The Jackson Laboratory 团队发现，STAT2 的 RNA 内含子保留会削弱干扰素信号，其剪接特征与肺癌患者 anti–PD-L1 免疫治疗响应相关。
来源：RNA-Seq Blog · rna-seqblog.com