medRxiv · All· C. Macedo, A., Aumont, E., Trudel, L., Hosseini, S. A., Therriault, J., Bezgin, G., Lebrun, A., Oliva-Lopez, D., Lussier, F. Z., Chan, T., Tissot, C., Rahmouni, N., Hall, B., Bizzi, I., Boccalini, C., Beker Godoy, J., Povala, G., Ferreira, P. C. L., Bellaver, B., Fernandez-Arias, J., Amaral, L., Ruppert, E., Scop Medeiros, M., Mroue, R., Rocha, A., Montembeault, M., Pascual, B., Masdeu, J., Gordon, B. A., Lowe, V. J., Oh, H., Soleimani-Meigooni, D. N., Fortea, J., Baker, S., Pascoal, T. A., Rosa-Neto, P. ·· 2 天前AI 评分26
Flortaucipir 与 MK6240 tau-PET 头对头比较：检测临床未受损个体中的轻微客观认知障碍
Head-to-Head Comparison of Flortaucipir and MK6240 tau-PET to Detect Subtle Objective Cognitive Impairment in Clinically Unimpaired Individuals
AI 导读
HEAD研究比较297名临床未受损个体的Flortaucipir与MK6240 tau-PET，发现两者均与轻微客观认知障碍相关。[18F]MK6240 SUVR越高，记忆越差；两种示踪剂的SEOT均关联较差记忆。MK6240体素级关联较Flortaucipir更广，相关性主要见于淀粉样蛋白β负担中高水平。
来源：medRxiv · All · medrxiv.org