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medRxiv · All· Roddy, E., Gold, L. S., Heagerty, P. J., Friedly, J. L., Rundell, S. D., Jarvik, J. G., Suri, P. ·· 2 天前AI 评分23

NSAIDs或阿片类药物会增加胫骨干骨折不愈合风险吗?

Do non-steroidal anti-inflammatory medications or opioids increase the risk of nonunion after surgical and nonsurgical treatment of tibial shaft fractures?

AI 导读

基于Merative Marketscan理赔数据的队列研究显示,确诊后30天内配取NSAIDs或阿片类药物,均与胫骨干骨折不愈合手术处理风险升高相关。纳入297,334名17–64岁患者,倾向评分匹配分析中NSAIDs组HR为1.60,阿片类药物组为1.41,二者无显著差异。

来源:medRxiv · All · medrxiv.org