medRxiv · All· Takayama, S., Yamazaki, K., Tsuchiya, T., Kanamori, H., Naoe, A., Kondo, Y., Watanabe, S., Yasui, T., Ogawa, E., Inoue, M. ·· 2 天前AI 评分54
CLEC10A标记神经母细胞瘤中T细胞富集邻域的MHC class II高表达髓系状态，并与MYCN非扩增亚型生存相关
CLEC10A marks an MHC class II-high tumour myeloid state that lies in T-cell-rich neighbourhoods, and its survival association is seen in MYCN non-amplified neuroblastoma
AI 导读
3个神经母细胞瘤队列共920个肿瘤的分析显示，CLEC10A标记的是MHC class II高表达、S100 alarmin程序较低的髓系状态，而非cDC2丰度。
来源：medRxiv · All · medrxiv.org